Abstract. On the basis of complex, interdisciplinary, systemic and selective approaches, methods of analysis and synthesis, a methodology for solving the problems of managing innovative factors of sustainable socially oriented economic development (SSODE) has been developed. It is represented by a structural econometric model for assessing the state and forecasting of innovative factors of the SSODE, is based on the formed system of socio-economic indicators for evaluating the subsystems of the management system of innovative factors of the SSODE, meets the criteria of stability, optimality and efficiency of management of economic systems, allows to assess the level of satisfaction of the vital interests of the population and make predictions based on the Modernized Human Development Index (HDI). The developed method of assessment and forecasting of sustainable innovative socially oriented development of the national economy consists in conducting a comprehensive analysis of the economic, social, and environmental subsystems of the system of management of innovative factors of SSODE based on the index method, factor and correlation-regression analysis and on two contours of the economic system corresponding to the conditions of stability (more than 61.8% of the population whose vital interests are satisfied) and instability (less than 61.8% of the population whose vital interests are satisfied). At the same time, in the first case, GDP per capita was chosen as the objective function, and in the second case, the human development index (HDI). The developed methodology will make it possible to formulate conclusions regarding the effectiveness of management decision-making by state regulatory bodies.