The article is dedicated to reviewing the potential of fungi of the genus Hericium in the context of sustainable development. Both theoretical and practical aspects of the application of these basidiomycetes are discussed. Particular attention is given to the possibilities of using these fungi in the field of healthcare, with a special focus on their neuroprotective, antioxidant, antimicrobial, anti-inflammatory, and other therapeutic properties. The article also examines cultivation strategies, nutrient medium selection, and optimal growth conditions that can ensure maximum yields of biologically active compounds with minimal environmental impact. The results of studies on the growth rates of Hericium strains in various nutrient media, including those containing cellulose-based components, are presented. It is shown that the most favorable media for achieving maximum growth characteristics of the studied fungal strains were malt agar and malt agar with the addition of cellulose-containing supplements: oak bark and fir needles, where the maximum growth rates were 5.5-5.7 mm/day.