The creation of clusters in modern agribusiness is a promising direction for the sustainable development of the country’s economy due to the possibility of obtaining advantages in optimizing production processes, increasing the efficiency of resource use, forming venture capital, and stimulating innovation. We propose to define a cluster as a set of industries that are combined vertically and horizontally to gain competitive advantages. The advantage of this approach is the focus on management and sustainable development processes. A cluster in agribusiness is a set of agribusiness entities that function as a system and achieve higher performance results based on complementarity, cooperation, and coordination of activities. We consider a strategic alliance to be a type of cluster, the main advantage of which is flexibility and the inclusion of companies from different sectors, projects and government organizations. Studies have proven the establishment and effective functioning of creative clusters in Ukraine, which contribute to the formation of an innovative environment and favorable conditions for the functioning of clusters in other areas. A model of cluster sustainable development in Ukraine is proposed, which allows the level of influence of a set of factors on GDP, in particular, equipment and technology, labor force, level of investment attraction, exports and imports, etc.